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Shaping the Future of Medical Imaging: Making "X-Nuclear" MRI Ready for the Clinic
When we think of MRI scans, we are usually looking at images formed by hydrogen atoms (protons) in the body’s water and fat. But there is an entire world of biological information hidden just out of sight. By tuning MRI machines to detect other isotopes — like Deuterium — scientists can track cellular energy processes in real-time. This field, known as X-nuclear Magnetic Resonance Spectroscopic Imaging (MRSI), holds immense potential for early disease detection and personaliz
Rachel Katz-Brull
2 min read


Tracking Brain Metabolism Without Radiation: How Deuterated Deoxyglucose Is Changing the Game
The ability to map glucose consumption in the brain has long been a cornerstone of modern medicine, particularly for spotting tumors, tracking neurodegenerative diseases, and mapping cognitive function. Historically, this has required Positron Emission Tomography (PET) scans using a radioactive tracer known as Fluorodeoxyglucose. While incredibly effective, PET scans come with explicit downsides: ionizing radiation, high costs, and a strict limit on how frequently a patient c
Rachel Katz-Brull
3 min read


Presentation at the ENC conference this year
In this year's Experimental Nuclear Magnetic Resonance Conference, the CortecNet team presented their success in synthesizing multiple deuterated 2-deoxy-D-glucose (DDG) analogs. The ENC conference took place in Asilomar, CA, USA, on April 12-16, 2026. The poster was uploaded to Zenodo with the DOI: 10.5281/zenodo.20703391 Abstract Deuterated 2-deoxy-D-glucose (DDG) MRI-based imaging agents Positron emission tomography (PET) using 2-deoxy-2-[18F]fluoro-D-glucose (FDG) is effe
Rachel Katz-Brull
2 min read


Insights and Highlights from the Annual Consortium Meeting 2025
The DDG-MRI partners met on December 1-2, 2025, for the annual consortium meeting. The meeting took place at the GE Healthcare campus in Munich, Germany. The partners exchanged results and ideas and met with the External Expert Advisory Board online. The project is on track with: Multiple deuterated 2-deoxy-D-glucose were synthesized at CortecNet and distributed to the partners. Initial in vivo studies at the University of Turin, Italy, and at Ulm University in Germany. The T
Rachel Katz-Brull
1 min read
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